LOT 2602-C123-10-001
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LOT VERIFIED
2602-C123-10-001
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INFLAMMATORY PATHWAY RESEARCH
KPV
99.83%
HPLC
Verified to the vial. Published to prove it.
In Stock ·
Lyophilized powder
·
Research use only
10mg
per vial
VOLUME PRICING
1
$75
Third-party verified ·
Freedom Diagnostics ·
Same-day ship before 12pm PT
COMPOUND DETAILS
01 — ABOUT THIS COMPOUND
KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of alpha-MSH, engineered to retain immunomodulatory and anti-inflammatory signaling properties without the melanogenic effects associated with the full-length peptide.In laboratory research models, KPV has been examined for its involvement in:
- Modulation of NF-κB–dependent transcriptional pathways
- Regulation of pro-inflammatory cytokine expression
- Peptide transport mechanisms mediated by PepT1 transporters
- Cellular signaling pathways associated with innate immune responses
KPV, the C-terminal tripeptide of alpha-MSH, has been documented to suppress NF-kB activation in intestinal epithelial cells and skin keratinocyte models.
Dalmasso G, et al. (Dalmasso G, et al.)."PepT1-mediated tripeptide KPV."Gastroenterology
Vavricka SR, et al. (Vavricka SR, et al.)."KPV intestinal inflammation."Gastroenterology
Cutuli M, et al. (Cutuli M, et al.)."Antimicrobial effects of KPV."Journal of Leukocyte Biology
02 — SPECIFICATIONS & VERIFICATION
Molecular Profile
CAS Number
67727-97-3
Appearance
White Lyophilized Powder
Solubility
Clear, Colorless
Sequence
KPV
3 residues
Independent Verification
Every lot tested independently by Freedom Diagnostics via HPLC-UV and mass spectrometry before release. Reports are publicly accessible and lot-specific.
Exhibit A.The trace.
HPLC-UV @ 220nm
·
Peak RT 0.27 min
·
Purity 99.83%
·
Freedom Diagnostics
·
LC-MS/MS identity confirmed
KPV
99.83%
$75